News

Medicine’s Dirty Little Secret

No, this is not about the vagaries of drugs, nor the immense pressure brought to bear on governments by the pharmaceutical behemoths determined to medicate everyone. It is about something discussed a number of times in this educational web site – Faecal Transplant Therapy.

Numerous people have utilised this mechanism to resolve persistent and life threatening conditions, in effect re-seeding their colon with bacteria from a healthy and willing donor can have dramatic beneficial effects – even if the process is challenging.

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What You Eat And Not Just The Number Of Calories, Is A Significant Factor In Diabetes Risk

New research in The FASEB Journal suggests that the postprandial levels of circulating metabolites in the blood of identical twins tends to be similar after a fast food meal, independent of weight difference.

If you think losing weight is enough to prevent Type 2 diabetes, don’t get your hopes up. A new research report in September 2014 issue of The FASEB Journal, suggests that you don’t have to be overweight to develop Type 2 diabetes. [1] This study compared genetically identical twins-one heavier and one leaner-and found that after eating a fast-food meal, the circulating metabolites, including those related to Type 2 diabetes, were found in both individuals at the same levels. These findings suggest that the onset of this type of diabetes is largely influenced by genetic factors and/or the composition of gut microbiota.

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Study Suggests Cinnamon May Be Used To Halt Progression Of Parkinson’s Disease.

Parkinson disease (PD) is a common age associated neurodegenerative disorder of the central nervous system[1]that was first described in an essay entitled “An essay of the Shaking Palsy” by James Parkinson in 1817. Clinically PD is characterised by resting tremor, bradykinesia, rigidity and postural instability. Causes for the disease are not well known however environmental, genetic, and immunological factors have been associated with the onset of this disease.

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Being Gluten-Free Linked to Less ‘Brain Fog’ in Coeliac Study

In a paper published in Aliment Pharmacol in Jul 2014, the symptom of ‘Brain Fog’ in effect a loss of cognitive clarity was resolved after going gluten free.[1]

Irene T. Lichtwark, PhD student, School of Psychological Sciences, Monash University, Melbourne, Australia, and colleagues examined the connection among a gluten-free diet, celiac symptoms, and cognitive function among 11 newly diagnosed patients with celiac disease (8 women and 3 men) aged 22 to 39 years.

The researchers tested patients for information-processing efficacy, memory, visuospatial ability, motor function, and attention before starting them on a gluten-free diet. The researchers tested patients again 12 weeks into the diet, and again after 1 year of adherence to the diet. The researchers conducted blood testing, intestinal permeability tests, and small bowel biopsies via gastroscopy at baseline, week 12, and week 52.

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Selected Lactobacillus rhamnosus GG Research Abstracts

Symbiosis between the gastrointestinal microbiota and the host is the basis for these health

benefits. In exchange for a stable environment and adequate nutrients, the microbiota play a role in maturation of the gastrointestinal tract, provide the host with nutritional contributions and help safeguard the host from harmful microbes. When this symbiosis is disturbed, introduction of naturally occurring intestinal microflora, like Lactobacillus rhamnosus GG, can assist in re-establishing homeostasis and optimal function.

 

To assist practitioners in the recovery of research papers that have utilised LGG as a primary organism for the determination of effects and outcomes, we hope this document will prove useful.

Once Broken; Difficult To Fix Microbiomes Have Long Term Consequences

The gut microbiomes of young children appear to fail to fully recover from the trauma of early-life malnourishment, even after they are treated with more-complete diets, according to a 2014 study published in Nature.[1]

In this paper the research team led by Jeffrey Gordon of the Washington University in St. Louis sampled the gut microbiomes of healthy and malnourished children in Bangladesh and discovered that the microbiomes of children who were underfed and whose diets lacked essential nutrients looked less like those of adults and more like those of younger, healthy children.

The findings present a possible explanation for the commonly observed complications that malnourished children suffer even after they are treated with a standardised food regimen, including stunted growth, cognitive delays, and immune system problems. The researchers have suggested that the immature gut microbiomes of malnourished children may be partially responsible for some of these long-term impairments.

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The Detox Summit

A group of health experts (very kindly including Michael Ash DO, ND, BSc, Dip ION) have been interviewed by Deanna Minich, PhD, FACN, CNS to provide a unique, considered set of opinions in the Detox Summit on the role that enhancing the safe and healthy biotransformation of endogenous and exogenous toxins and related cellular by products has on health promotion goes live on August 4th for one week. To support this series of interviews the proposals and recommendations will now be anchored into ACTION in the form of the newly-created, Detox Challenge, a 21-day Functional Medicine-based detoxification with an emphasis on nutrition, environment, behaviours, and mental-emotional patterns.

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Boost Brain Function: PRPS Are Beneficial Neuro-Cytokines That Protect The Brain

Can proline-rich polypeptides (PRPs) protect your brain and even boost brain function? Studies in vitro on animals and humans support that idea. The neuro-protective cytokines in PRPs have a remarkably stabilizing effect on cognitive function in Alzheimer’s disease patients. In vitro studies show that PRPs inhibit fibrils and amyloid plaques.[1] PRPs also modulate intracellular levels of reactive oxygen species (ROS), by regulating glutathione metabolism and antioxidant enzymes.[2] Gene expression analysis found that PRPs down-regulate genes involved in inflammatory pathways and increase levels of an Amyloid-beta (Aβ) hydrolyzing enzyme.[3] When given orally to mice, PRPs improve motor and sensory activities.[4] When mice are given either PRPs or plain colostrum, the PRP supplemented mice swim faster to a hidden platform.[5] PRPs also improve spatial learning and memory in older rats.[6]

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Mitochondrial Medicine: Diving Deep into the Secrets of Cellular Health

As basic science and clinical research cross paths, a new understanding of the importance of mitochondria in health and disease has emerged. On March 20, 2014, FOCUS moderated an international Skype conversation between Michael Ash, BSc, DO, ND, F.DipION, and Alex Vasquez, BS, DC, ND, DO, FACN on the new epoch of mitochondrial medicine. Michael Ash is co-founder of Nutri-Link Ltd, a subsidiary of Allergy Research Group, LLC. Endnotes that reference relevant studies and sources have been added for readers and physicians.

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Building Bone: The Novel Role of Tocotrienols

An Interview With Professor Dr. Ima-Nirwana Soelaiman, MBBS, PhD, Deputy Dean (Research and Innovation) Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Biography: The focus of Dr. Ima-Nirwana’s research is the impact of natural products on bone metabolism and osteoporosis, with special emphasis on tocotrienols. Dr. Ima-Nirwana has published 122 articles in scientific journals. Together with her team she has presented her work at over a hundred local and international conferences.  The results from her animal studies have consistently shown that tocotrienols can prevent and reverse osteoporosis due to stressors, including menopause, estrogen and androgen deficiency, steroid excess, nicotine exposure and oxidative stress and inflammation. She is currently planning clinical trials on tocotrienols and osteoporosis in the USA and in Malaysia. She is a member of the Malaysian Osteoporosis Society and the Malaysia Endocrine and Metabolic Society. She holds a patent within Malaysia for the use of tocotrienol for bone health in humans.

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