Researchers Pinpoint How Vitamin D May Help Clear Amyloid Plaques in Alzheimer’s Disease
Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signalling networks to help stimulate the immune system to clear the amyloid-beta protein.[1]
Previous laboratory work by the team demonstrated that specific types of immune cells in patients with Alzheimer’s disease may respond to therapy with vitamin D3 and curcumin, a chemical found in turmeric spice, by stimulating the innate immune system to clear amyloid beta. But the researchers didn’t know how it worked.
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Parkinsons and Faecal Transplantation – or at least resolution of constipation!
Faecal bacteriotherapy, now termed faecal microbiota transplantation (FMT), has gained prominence in light of the recent epidemic of Clostridium difficile infection (CDI) in North America and Europe. Coupled with the emergence of a hypervirulent strain of C. difficile, FMT is likely to feature prominently in the treatment of both relapsing and severe C. difficile colitis. Given that FMT is capable of successfully reversing CDI-associated colitis and is arguably the most complete and ideal probiotic, one can see the potential value of FMT in other bacteria-mediated diseases.
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Dr Tom O’Bryan: Nutrigenomic Therapies for Autoimmune Disease.
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Leaky Gut May Be The Primary Mechanism For Autoimmune Activation?
In January 2011 a very interesting paper was published in Physiological Reviews, exploring the role of gastrointestinal permeability, genetics and risk of development of autoimmune diseases.[1]
This abstract explores some of the principle messages in the paper which is also available as a full free text.
It is generally accepted that it is the interplay between environmental factors and specific susceptibility genes that underlies the aberrant immune response responsible for the onset of these diseases. Less than 10% of those with increased genetic susceptibility progress to clinical disease, suggesting a strong environmental trigger in the predisease state.
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Does Avoiding Allergens When Pregnant or Breast Feeding Confer Any Benefit
It has been considered over the last few years to advise mothers during pregnancy and whilst breast feeding to avoid allergenic foods such as milk, nuts, and other risky foods to reduce the risk of childhood allergy. Not for the first time researchers say this practice may be doing more harm than good. Research papers presented at a recent American Academy of Allergy, Asthma, and Immunology conference suggests that exposure may be better than avoidance.[1]
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High-Dose Vitamin D May Alleviate Menstrual Cramps: Study
Women who experience painful menstrual cramps could find relief from high-dose vitamin D3, according to new research – which suggests the dietary supplement could provide an alternative to painkilling drugs that are currently used.[1] Women with a history of severe menstrual cramps reported significantly less pain when they took an ultra-high dose of vitamin D five days before their next expected period.
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So How Much Vitamin D do I Need?
In practice life a number of questions arise relating to all supplemental suggestions and vitamin D is no different.
• What do I need to be healthy?
• How do I know what my levels are now?
• How do I raise my levels if I need to?
• What foods, supplements or lifestyle changes do I need to do?
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Glycophospholipids and their Effect on Fatigue
Michael Ash interviewed colleague Dr Rita Ellithorpe MD for CAM on the clinical application of a patent pending form of phospholipids known as glycophospholipids and commercially sold as NT Factor and referred to as Lipid Replacement Therapy® (LRT®).
Unusually for many food supplements, glycophospholipids have been the primary ingredient in a number of research papers, some of which has had Dr Ellithorpe as a primary contributor. Her colleagues in this work have included Prof Garth Nicolson and Dr Settenari. References relating to some of these studies may be found at the end of the interview. LRT® is scientifically validated in 9 preclinical and clinical trials over the past 15 years, with millions of doses safely taken by consumers. More than 25 articles in scientific and medical journals have been published on its benefits.
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The Benefits Of Vitamin D On Gait, Muscle Strength And Balance In Older Adults
The usefulness of vitamin D is increasingly being explored and as a result better studies are being collated and brought into publication. A study published the Journal of the American Geriatric Society in Dec 2011 reveals that Vit D status is linked to physical functionality and represents a suitable replacement option. Whilst the dose recommended is modest, it is able to record an improvement, higher levels may provide greater benefit depending on base line levels.
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Amla: An Ancient Super Berry Emerges from India
The most revered medicinal berry in the entire subcontinent of India—Amla berry, or Emblica officinalis—is said to come from the first tree to appear on earth, manifested out of the tears of Brahma while he was meditating.[1]
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