IBS Relief and Probiotics – They do Work
Probiotics are widely consumed and the widespread advertising is often not really justified by the evidence. Many products were never studied as such and some companies use studies performed with other (and different) products for advertising.
In the March edition of GUT a systematic review on the randomised control trials (RCT) undertaken so far suggests that many are of good quality.[1], they determine that meta-analysis is impossible due to the various strains, phenotypes and genome vary greatly.[2] As a consequence and as stressed by the FAO/WHO joint report the benefits of one probiotic ‘cannot be extrapolated to other probiotic strains without experimentation.[3] However there tend to be properties consistent with different groups, from which strain specific organisms may be extracted.
Read the rest of this page »
Gut Bacteria May Make You Fat
Obesity: A consequence of adverse inflammation & microbial disruption?
By Michael Ash BSc(Hons) DO, ND, FDipION
Published in CAM 2005
Overweight and obesity are serious, chronic medical condition associated with a wide range of debilitating and life threatening and economically burdensome conditions. The recent and extensive increases in obesity among Europeans are eroding many recent health gains.
Paradoxically the economically wealthier communities of the world continue to over consume food and food products, whilst other nation communities still suffer from food deprivation and starvation, due in the main to drought, floods, ‘acts of God’, corruption and conflict. Approximately 9.5% of the global burden of disease is currently attributable to being underweight,[1] whilst there are now hundreds of millions of people (>500) in developed and developing countries that are overweight or obese. This condition of excessive weight is now so common that it is rapidly replacing malnutrition and infectious diseases as the most significant cause of ill health[2]. An escalating global epidemic of overweight and obesity – “globesity” – is taking over many parts of the world.
Read the rest of this page »
Dysbiosis – What Have We Learned?
Michael Ash BSc(Hons) DO, ND, FDipION reviews some of the last 12 months of published research.
The human body has some 10 trillion human cells—but 10 times that number of microbial cells. So what happens when such an important part of our bodies goes missing or never develops?
Plus what can we do to limit any adverse consequences linked to microbial disruption – referred to as dysbiosis?[1]
Further, do probiotics—dietary supplements containing potentially beneficial microbes actually support appropriate immune responses?
Read the rest of this page »
All Immunity is Mucosal – The GUT is No 1
The Gut is The Formula 1 of Immunity
Properly regulated mucosal immunity is critical to overall health and well being. The cells found in the mucosal surfaces of the body meet on a daily basis, local challenges from foods, microbes and environmental pollutants. The result is a series of immunological decisions that on a single day exceed those made by the systemic immune system in a lifetime.
The immune system bound up in these tissues – mostly the ‘innate immune system’, must translate this infornatic onslaught to the ’systemic immune system’ affecting the body as a whole. Immune tolerance or homeostasis in these tissues will help ensure adequate nourishment from passing ‘foreign’ food stuffs and so maintain bacterial/commensal balance. It is this bacterial balance that will ensure immunological tolerance so keeping the balance of power in the hands of health promoters (commensals) via this yin and yang relationship.
Read the rest of this page »
Dissolve Biofilms With Fibrinolytic Enzymes: Autism Support
A Novel Approach to Chronic Infection in Autism Spectrum Disorders
An Interview with Peta Cohen, M.S., R.D., founder of Total Life Center in Northern New Jersey. Cohen specializes in treating children with autism using a biomedical / nutritional model. Cohen received her Masters in Clinical Nutrition from New York University and has been a Defeat Autism Now! practitioner for the past ten years.
Read the rest of this page »
Lactobacillus GG: A Potent Immune Regulator Effective in Many Disorders
New Research Reveals Probiotic’s Anti-Toxin, Anti-Inflammatory, Immune Boosting Properties
Lactobacillus GG is the most prolifically researched probiotic in the world—over 400 studies have been published that document its remarkable immune-modulating properties.This unique immunobiotic was isolated from a healthy human in 1985 by a team of two Tufts University researchers,Barry Goldin, M.S., Ph.D. and Sherwood L. Gorbach, M.D. They spent nearly a decade testing organisms until they discovered one that was a potent antimicrobial, survived stomach and bile acid, and was very, very sticky—it adhered well to the gut mucosa.
Read the rest of this page »
LGG (Culturelle) Its Workings Are Explained
Valio’s Lactobacillus rhamnosus GG (LGG®) is the most frequently studied and used probiotic. Under the supervision of researchers at the Institute of Biotechnology, and the Department of Basic Veterinary Sciences at the University of Helsinki, an international research team determined the genome sequences of LGG and a bacterium closely related to it. The results, published in the renowned PNAS journal, shed light on the origin of probiotic mechanisms.
Many research publications have confirmed that bacteria promote health and support immune systems and improve digestion. Some probiotics can also alleviate the symptoms suffered by those with irritable bowel syndrome. As many as every fifth westerner suffers from this pain, also called spastic colon. Studies say that LGG probiotics are also an effective treatment method for reducing children’s atopic symptoms, and the risk of respiratory infections.
Read the rest of this page »
A Novel Approach to Treating Depression – How Probiotics Can Shift Mood by Modulating Cytokines
Michael E. Ash, BSc.(Hons) DO. ND. F.Dip ION has written an overview from a clinical perspective of the emerging science related to the mucosal immune system and the health of the brain in relation to affect. Published by the in house journal from Allergy Research Group it provides a strategic approach to managing individuals using a novel probiotic strategy.
From our early days in utero until we die, the ability of the GI tract to renew and replenish itself and maintain a stable relationship with trillions of bacteria is astounding. On a typical day the innate immune system of our gastrointestinal tract will process more immunological information than the rest of our body in its entire lifetime. It’s an absolute immunological miracle we can consume antigenic particles of food and not drop down dead every time we do so.
Read the rest of this page »
Bonnie Bassler on how bacteria “talk”
See original post
Microbes: What They Do & How Antibiotics Change Them
Antibiotics and antibacterials can do more damage than good when they:
- kill good bacteria inside the human body
- destroy microbes that clean up pollution
- lead to antibiotic resistance in microorganisms
- make treatment of some diseases difficult when overused
Dr Maura Meade-Callahan PhD presents a summary article to explain further.
