Vit D Optimisation Requires Supplementation Says Harvard

logo-HHP_mastheadThe conservative Harvard Medical School in the USA normally promotes micronutrient intake being derived from food stuffs alone. The Health Publications Bulletin out in Sept 2009 says that from the perspective of Vitamin D food sources may be inadequate and that supplementary intake is required to meet physiological optimisation. (See Video)

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The Role of Vitamin C in the Treatment of the Common Cold

generic.Par.0001.ImageDr Harri Hemila MD PhD co author of the Cochrane Review article replies [1]:

The Cochrane review was limited to placebo-controlled trials in which at least 0.2 g of vitamin C was used per day.[2] Most of these trials examined vitamin C administration as regular supplementation and provided strong evidence that vitamin C shortens the duration of colds and alleviates its symptoms.

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Complementary and Alternative Medicine: Herbs, Phytochemicals and Vitamins and Their Immunologic Effects

S0091674909X00102_cov200hComplementary and alternative medicines (CAMs) are used in more than 80% of the world’s population and are becoming an increasing component of the US health care system, with more than 70% of the population using CAM at least once and annual spending reaching as much as $34 billion. Since the inception of the National Center for Complementary and Alternative Medicine, there has been an enormous increase in the number of basic science and therapy-based clinical trials exploring CAM.

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Vitamin C as a Potential Anti-Cancer Agent: Progress and Controversies

suppl.1.coverVitamin C is commonly known to be essential to human health. However, specifically as it relates to cancer treatment, the value of vitamin C is debated and often considered a topic of scientific controversy. Cancer researchers have investigated various ways of administering high-dose vitamin C, including both orally and intravenously. Researchers have also examined different forms of vitamin C—ascorbic acid (AA) and dehydroascorbic acid (DHA)—which may well be a comparison of apples and oranges.

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Does Diet Have a Role in the Aetiology of Rheumatoid Arthritis?

Although dietary factors have been extensively studied in many chronic diseases, the role of diet in the epidemiology of rheumatoid arthritis (RA) has received little attention. Fruit and vegetables and dietary antioxidants are thought to play a protective role in the pathogenesis of CVD and some cancers, but few studies have investigated these dietary components in the aetiology of RA.

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The Role of Meat in the Expression of Rheumatoid Arthritis.

Rheumatoid arthritis (RA) is characterized by inflammation of the synovial tissues in the joints. A number of papers related to dietary components that are associated with this inflammation are reviewed. In addition, the ecological approach is used to study the links between diet and RA. Multi-country data for prevalence of RA for females from eight and fifteen countries were compared statistically with components of national dietary supply.

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The Role of Diet in Susceptibility to Rheumatoid Arthritis: a Systematic Review.

OBJECTIVE: Many studies have examined the role of diet in the management of established rheumatoid arthritis (RA), warranting several recent reviews. However, none have considered the possible link between diet and the onset of RA in detail. Studies investigated a possible effect of individual components of diet and the development of RA, but the lack of a systematic review means there is no unbiased assessment of the evidence.

METHODS: We systematically reviewed studies with comparison groups that examined dietary intake or biological markers prior to the onset of RA. Four electronic databases were searched to identify relevant reports. Six quality criteria were agreed, against which the studies were assessed. The main outcome measure was a diagnosis of RA according to the ARA 1958 or revised ACR 1987 classification criteria.

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Impact Of Antioxidant Supplementation On Chemotherapeutic Toxicity: A Systematic Review Of The Evidence From Randomized Controlled Trials.

Much debate has focused on whether antioxidants interfere with the efficacy of cancer chemotherapy. The objective of this study is to systematically review the randomized, controlled clinical trial evidence evaluating the effects of concurrent use of antioxidants with chemotherapy on toxic side effects.

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Antioxidants And Other Nutrients Do Not Interfere With Chemotherapy Or Radiation Therapy And Can Increase Kill And Increase Survival, Part 1.

PURPOSE: Some in the oncology community contend that patients undergoing chemotherapy and/or radiation therapy should not use food supplement antioxidants and other nutrients. Oncologists at an influential oncology institution contended that antioxidants interfere with radiation and some chemotherapies because those modalities kill by generating free radicals that are neutralized by antioxidants, and that folic acid interferes with methotrexate. This is despite the common use of amifostine and dexrazoxane, 2 prescription antioxidants, during chemotherapy and/or radiation therapy.

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Antioxidants prevent health-promoting effects of physical exercise in humans

Abstract: Exercise promotes longevity and ameliorates type 2 diabetes mellitus and insulin resistance. However, exercise also increases mitochondrial formation of presumably harmful reactive oxygen species (ROS). Antioxidants are widely used as supplements but whether they affect the health-promoting effects of exercise is unknown. We evaluated the effects of a combination of vitamin C (1000 mg/day) and vitamin E (400 IU/day) on insulin sensitivity as measured by glucose infusion rates (GIR) during a hyperinsulinemic, euglycemic clamp in previously untrained (n = 19) and pretrained (n = 20) healthy young men. Before and after a 4 week intervention of physical exercise, GIR was determined, and muscle biopsies for gene expression analyses as well as plasma samples were obtained to compare changes over baseline and potential influences of vitamins on exercise effects.

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