Perilla Targets Inflammation: Joins Traditional Gut Nutrients as Potent Anti-spasmodic and Anti-inflammatory

The remedies for gastrointestinal complaints are legion and stretch back far in human history. Ancient Chinese physicians prescribed anise for flatulence, while Dioscorides, chief physician for the Roman army, recommended garlic for parasites. Many are effective and stand the test of time, but contemporary scientific research on novel extracts offers up surprising new finds. The Asian plant, Perilla (Perilla frutescens) for example, offers valuable assistance in the management of functional gut problems.

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SCFAs – A Treatment for Gastrointestinal Inflammation?

As each month goes by the dynamic and intersecting relationships between our gastrointestinal organisms and the food we consume continues to open all sorts of opportunities for comprehension and treatments. Faced as the western and many non-western cultures are with the expansion of non-communicable diseases and inflammatory disorders, the idea of simply suppressing a abnormal response to a common trigger is losing some of its appeal – there is no doubt that pharmaceuticals have tremendous clinical benefits, but faced with the decision to use a drug every day for life, or to make lifestyle changes – many people are opting for the lifestyle option.

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Avoiding Gluten Hastens Weight Loss

But…. it also appears to offer far more than simply compressing overall body mass. For some time the world of gluten sensitivity as well as the pathology coeliac disease have been experiencing a substantial amount of increased scientific and lay interest. The long held critique that most Nutritional Therapist suggest avoiding gluten in the absence of CD is a needless and just a fallacious recommendation has come under increasing credibility attack.

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Faecal Transplant (FT) and IBD

I have explored the role of appropriate transplantation in the resolution of MRSA infection that fails to resolve with antibiotic therapy, and have intimated that other conditions of the bowel and linked tissues may also benefit. The model is: that loss of mucosal tolerance underlies the pathology of inflammatory bowel disease and is also linked to irritable bowel syndrome. These altered states of function reflect a combination of environmental, genetic and emotional events that coalesce into a wide range of conditions.

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Milk Fats Plus Bacteria = Gut Inflammation

It is a global phenomenon – the increase in gastrointestinal inflammatory disease over the last 50 years, so fast is this occurring that genetic drift is very unlikely to be attributable as causal; but it is likely that changes in diet and lifestyle amongst the genetically susceptible act as triggering agents to induce aberrant immune responses that lead to inflammatory bowel disease and other systemic inflammatory illnesses.

In a fascinating study published in Nature on the 13th June in their letters section a group of researchers show how the inclusion of fats derived from ilk, change the bacterial composition in the gastrointestinal tracts of mice promoting the development of colitis.[1]

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Fatigue, Immunity and Inflammation:– Their Resolution Using Natural Medicine.

Michael E. Ash BSc DO ND, Robert Settenari M.S and Prof. Garth L. Nicolson Ph.D explain the relationship between energy deficit, mitochondrial membrane quality, the immune system, inflammation and how to recover from persistent fatigue using validated natural medicine.

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Probiotics Can Make Dendritic Cells Stop Singing the Blues

GUT is one of my favourite journals, as they regularly explore the ‘alternative’ approaches to colon health management with a vigour that appeases the clinician in me, and a rigour that calms the scientist.

A paper published in early 2012[1] add’s further knowledge to the role that probiotics and the active components produced by lactic acid bacteria have on mucosal health and intestinal balance. An especially pleasing discovery – for an old long term user of this word – is their inclusion of the term dysbiosis, with a summary explanation in the opening paragraph, as there is no abstract. I have reproduced it below:

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IBS And Food – Is There A Link?

There is a growing body of evidence to suggest that certain dietary constituents exacerbate symptoms and perhaps contribute to the pathogenesis of IBS. Patients have long associated their IBS symptoms with the ingestion of certain foods, combinations of foods, or generally with meals. Response rates from elimination diets have ranged from 15%-71%,[1] with wheat, milk, and eggs being the most commonly implicated foods.

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IBS Succesfully Managed by Nutritional Therapy

It will be of no real surprise to know that the incidence of irritable bowel syndrome (IBS) is common. Around the world it is estimated that some 10-20% of the population suffer from it. This is not an inconsequential number, and apart from the miserable statistics, it comes with loss of function, misery, anxiety, pain, bloating, altered bowel habits and loss of quality of life.

Whilst a clear explanation of the cause remains somewhat elusive, there is an increasing acceptance that the relationship between the brain-gut axis, central nervous system, peripheral stress response, infection, dysbiosis, barrier defects, inflammation and immune imbalance play significant roles in the causation.

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Is this a Perfect Functional Meal for Mucosal Tolerance?

Stewed apples as medicine

 

Functional and pathological digestive tract conditions reflect a change in the relationship between the host microbiota and the mucosal immune and nervous system. These result in a wide range of distressing symptoms for which there are a variety of strategies, but no single intervention of consistent benefit. A component of patient care we sometimes overlook is that of the application of therapeutically relevant foods. For over 20 years I have been using a tried and tested formula that contemporary scientific research is now explaining why it has proven so effective for many patients.

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