Oestrogen Metabolism is Beneficially Manged By Plant Extract (DIM)
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Diindolylmethane (DIM)
A phytonutrient and plant indole found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale, with potential antiandrogenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial oestrogen metabolism in both sexes by reducing the levels of 16-hydroxy oestrogen metabolites and increasing the formation of 2-hydroxy oestrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. Check for active clinical trials using this agent. (NCI Thesaurus)
