A Novel Approach to Treating Depression – How Probiotics Can Shift Mood by Modulating Cytokines
Michael E. Ash, BSc.(Hons) DO. ND. F.Dip ION has written an overview from a clinical perspective of the emerging science related to the mucosal immune system and the health of the brain in relation to affect. Published by the in house journal from Allergy Research Group it provides a strategic approach to managing individuals using a novel probiotic strategy.
From our early days in utero until we die, the ability of the GI tract to renew and replenish itself and maintain a stable relationship with trillions of bacteria is astounding. On a typical day the innate immune system of our gastrointestinal tract will process more immunological information than the rest of our body in its entire lifetime. It’s an absolute immunological miracle we can consume antigenic particles of food and not drop down dead every time we do so.
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Bonnie Bassler on how bacteria “talk”
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Enzyme Therapy & Cancer – Recent Paper Questioned!
Pancreatic Proteolytic Enzyme Therapy Compared With Gemcitabine-Based Chemotherapy for the Treatment of Pancreatic Cancer.
Dr Gonzalez, a recent expert speaker at one of the NL expert education seminars, has had his therapy heavily criticised in this recent article published in the respected Journal of Clinical Oncology.
At first sight it can seem that the paper roundly demolishes the pancreatic enzyme and lifestyle treatment recommended by Dr Gonzalez, and adds considerable value to the mixed chemotherapy treatment provided as the competing arm of the therapy.
In fact this paper has already been lauded in the arenas frequented by the more committed anti-alternative or non RCT evidenced medicine as a gross failure of the enzyme therapy to show any benefit in the care of pancreatic cancer patients.
Surely this must be considered an experts review, especially as the lead author Dr John Chabot was the appointed independent trial Principal Investigator at Columbia? He would know and report accurately what went on – wouldn’t he?
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H1N1 (Swine Flu) What Does it Mean This Winter?
The European Centre for Disease Prevention and Control recently surveyed H1N1 (Swine Flu) epidemiological 2009 data for 28 countries, finding that 51% of all deaths have been among people aged 20-49 years, and only 12% were among people over 60 years of age.
This is striking, as it is a near-perfect reverse of normal flu trends, and mirrors what was seen, demographically, in 1918. While the President’s Council of Advisors on Science and Technology have tried to factor in such trends, it is extremely difficult to know how influenza dynamics, illnesses and death rates may vary if transmission and illness is primarily among young adults.
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Ghostwriting Is Called Rife in Medical Journals – Still!
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Six of the top medical journals published a significant number of articles in 2008 that were written by ghostwriters, according to a study out on Thursday 10th September by editors of The Journal of the American Medical Association. This was then reported on in the New York Times, from where the essential elements of this post were extracted.
Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
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Foxp3+ T regulatory (Treg) cells control all aspects of the immune response. This paper reviews the in vitro model systems that have been developed to define the mechanisms used by Treg cells to suppress a large number of distinct target cell types.
Oestrogen Metabolism is Beneficially Manged By Plant Extract (DIM)
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Diindolylmethane (DIM)
A phytonutrient and plant indole found in cruciferous vegetables including broccoli, brussels sprouts, cabbage, cauliflower and kale, with potential antiandrogenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial oestrogen metabolism in both sexes by reducing the levels of 16-hydroxy oestrogen metabolites and increasing the formation of 2-hydroxy oestrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. Check for active clinical trials using this agent. (NCI Thesaurus)
Zonulin, Leaky Gut and Coeliac Disease – The Mystery Unravels
In 2000, researchers from the University of Maryland School of Medicine identified that a protein called zonulin was a critical molecule in the development of coeliac disease and other autoimmune disorders including multiple sclerosis and diabetes. This relationship further links the risk and progression of systemic disease to the health of the gastrointestinal tract.
Zonulin has, as is typical in the history of immunology been further clarified and renamed as haptoglobin 2 precursor.
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Is Mercury Toxicity an Epidemic?
Date: 27/7/2009
Is Mercury Toxicity an Epidemic? Author: Joseph Pizzorno, ND
Source: Vitamin Retailer Magazine
Conventional medicine has dismissed mercury toxicity as a clinical concern except in cases of obvious poisoning. This is due to the poor correlation between the various measures of mercury body load and clinical symptoms. It is also the reason the dental community has in the past so consistently denied that amalgam fillings are a health risk. (Although called “silver” fillings, they are actually about 55 percent mercury.) However, the integrative medicine community has for decades believed that chronic low-level mercury exposure is the root cause of many chronic diseases ranging from autism to heart disease to “brain fog.”
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One Jab Appears to be Effective for H1N1 – Says Preliminary Report
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Leaving aside the questions concerning the validity of receiving the new H1N1(2009) vaccine in terms of need, and whether there may be as yet to be discovered risk and side effects that are greater in health impact that the actual virus. The questions about does it actually induce immune defenses against the H1N1 virus are now starting to be answered.
The immune system is prone to the same grave misfortunes as any defense system handling weapons: collateral damage that comes with the destruction of the enemy on one’s own territory and friendly fire due to mistaken identity. Whereas the collateral damage is the price we pay for clearance of infections, autoimmunity is a pathological process. Nevertheless, the effector mechanisms involved in both processes are the same. Whether environment can be a cause, a trigger or an amplifier of an autoimmune disease are questions that are being intensively investigated.
